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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106d3281619437adb0f47d7cbdea73d398921d8034aa0a278f7703da5d25b16d' 
  AND token = '8Z6hqpD9qG3H5eK4waAhP6Cb9SMEzWFDn741+yxfvFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}