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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ee9e65b394a8de3825e59946ab3502f111004cc04ccb25ca79955aeb6e5590e' 
  AND token = 'ES3PqZX1m3vQAawlnLzhasp3vSoN84UYF4gb7B/bWiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}