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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ffdb78003bea4ef5e201a61f7bdc6f221fd1d2cd683fd3554d7e6f1b255fe27' 
  AND token = 'SXsawwCPCQoGIOCSwBbWGvHNwF6D0NHwN272UDYO5I4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}