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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f78b56968b8041555589c392d6da7b59276a525f34ae6243ddde13ec8b3d101' 
  AND token = '2vYgdB4KKeAutEQIykU8NZnCF0AK9Sd/No98B+x+vdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}