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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405c9e2e83e89d366f01cf1500fd850fd62639c1b548be9c8667af73e26892ff' 
  AND token = 'j3AeZ3+Rjm8sjKyYfjATkUk9Z3SABy5EZBb3kEXpiFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}