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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad86c7a3b58184eb886a2fbe0f176b138967417a028f8241f60ed66fc2b53a8c' 
  AND token = 'jk60v9Unj+qEMLXVj1EmU3qbRh0IS3SDZ7HdU9sFsh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}