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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64e78c08053b7f0bd502773025325f6f7835b2355d6a0614e705f19dafcdd5b8' 
  AND token = '1lE6JIVSU2GU7Krt8f+ho+qmeLm8/9u+y4cuZ21GEMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}