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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0573f977122195b8f277d26a9eab7765160dc4f603f373565a4f9744a53197' 
  AND token = 'TR2CbENF2/cN1tvip7N1oLZNWOhVmZ1Lo0BsGRky/oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}