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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe1f38af13a848fd0e0aeb661d40d10724aed1ead2b3f575e0f3583e937d05c4' 
  AND token = 'UL/TJaQFpRgregnYvt7z7IN3vnsVimT6rI8oFZBjbB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}