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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1bfae52d7bf1f6526b8efa1904739e2d5824935833387407fc4b2598d6dc022' 
  AND token = 'IM46Nzb7M8N+HEAw9PWfEvQf1xyuhj1b8bAvgS2rSGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}