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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0a2f4864619162109b971972156cd0fb38deff146a2697fca1f4681fcff07f0' 
  AND token = 'JwSuTkSTnRKW2lDUCdW6RdWpfe8EfFcD3JTzt9X/UAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}