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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ecdc3e701e7970650fc4fb0045720f2427dec31e8227063bb2a01fdf51e4bb' 
  AND token = 'T2Ian6ArsJ5O+4WyyxDLOFrPzqq5FXVFv8zh6Ej40JM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}