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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0efde178838651c4b751539626390c970122d721c35d45f4c22236eeada27a69' 
  AND token = 'aOhKc+o9OWu3GCMAj23CRWOo5JioY5sfEkFiIjP7vK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}