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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41284f388b52a7c4df3bc94e7e43185d767f72ea51a70ee662d290aa4f90f574' 
  AND token = 'Bx5kF/s0OhY7U7HJjO6ulBTFBb4Umilw6tZ24uPn/Z8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}