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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0acbb5f54ce84c7957bab04d5970e3c40b2ac3bf25b88c36c26a2c9586f5b29c' 
  AND token = 'OxadGfnGJZAE+srbKZSg+cIA6NZ0RPfw4JoN4FkKX3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}