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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8c609af5284d9e5759639293013e2e032ee24c732f6e5d505af3b65e83bf2c' 
  AND token = 'zMDUhhzLJVRcriqmUnOcHcEisqmRmW9IFfZ+tfPf8vE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}