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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2236069d3fa01d4093317bf13afc3748fc580abde2c5d281274ab09bbe7b2585' 
  AND token = 'onoZB18E7Mf2cb+5PfYOox97Py1iMyANSM9U4stvpoA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}