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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '888f5687c5c9f4960a89ab04d8e05a374fb3b5cd6d9ce35cc55ffeff525d59c9' 
  AND token = '0F5ChrR0z2A7SAvJ83zLZ70Us5xwv0uVpoueaZNaMT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}