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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d8649a5ec19924326677d3c90d971a0cd3e2304739c9c11e7fd509aec00c714' 
  AND token = 'alIqc+s1qDeog/xluqShz71/5gM7sDn4EkJec0sxgyU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}