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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ef9b5d0db7cb09abe8fef1fd74ff7b78936f668b893a7b0fe8f206ed7212b82' 
  AND token = 'JyBYVLIZdEV80LWvqaBN+u6xMSJB7+762BtfOenpw0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}