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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '263f327ac5d138ac3047d3654625cd9e73cb1f05253d514e23b4c6a5e5c9e769' 
  AND token = '9Du38vlxWkLbjAQ3n4KR6rAHTdr5GOYdsUTMESRCmUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}