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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63b445c289688264f3eb4d1480d267ac06ee49f9b4b42d37136727a9c1c00ef9' 
  AND token = 'mFV9Kz1fdlKPgomtyCk/1wKcGMm1bU5UR7R0r+wAWME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}