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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c85d200d180ff32c34f46c260265d1973cc5f8048df5485111b301e369440c29' 
  AND token = 'aex82cVf+xydkDGzAoZG1xD6suQfODVXneit8ibONDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}