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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490165a60be3f337aaf84dd5a9eb4f7834bd4bb664bd813e2f4174266283e3b8' 
  AND token = '/nOnpXZ4ML+ZEwAzSeYoHudcexxvYY/Yt2k2uK16nX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}