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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75dbf32e0ee857598110f139c89b72501712aee5104b89b6d1892836705a5d22' 
  AND token = 'gNaYf13Ajf9zU5sEmspmsswxo23LAjSI1KVFdN5CYbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}