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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '589bd6c932d3ce7f6416f30d7e877e07e46455df0860e345666fdb4146e1ec03' 
  AND token = 'DMMpYLpLbnKIgYJRNIS4DmhiTLysxfIEpVkHnuV4PEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}