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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '736ab3915c2c529b06448d53229a80a7387ed7fc1cfbe5a8a4828c6eb5e2c8e8' 
  AND token = 'IcucQYI9O5T79cl/syynY3Z/5ArZE+TYNlHLCmKDSg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}