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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43869f29e07fc632b44465b1ed52ebf493732a414839c75c974ac6382881426' 
  AND token = 'FEgQukx1j9kwXtQCgllqrTJ6uE0xo2w/pB1RsAcMSZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}