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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c5820e088a60ccb6b2ab088b5fd22aa5607d24584ba2f6f02f5a7be6495146' 
  AND token = 'FCHqBuN+2BHoeLFefB94CHq2X0R8aS1bxFvjVkna8xE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}