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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbea58763acd855e5f3f88422814b22a66edb15a60c537e5a65094c4a0531d48' 
  AND token = 'kp28JyMFVix5Tb0ZS+/DhMD1NW+DmZDG66aHEjtmSy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}