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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ec7afd09cea8e99fe5867d8fa3951a43279b830e75feece01d4890dde0ccd7' 
  AND token = '9xbY3LxXjPlvhMZ5vhsWRQZxNKThMO7/wG5U4P4q8Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}