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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7868b1cd54292b0bf638ec48bde050f12135b5e976127e7bd8ccdb7f60df702e' 
  AND token = 'V6L+l6Wg2GWWv+6IlefUf7+FLI6xVZSKoejDhAN9PDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}