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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cc8f21018e15f78310548d66eac9e86c550f01c62fa3e25f9c6f79932d57938' 
  AND token = '6L4qvcRpVwAoAsR9hmh8r6kRzhiTR2vHRCKjCCp2WKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}