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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a0a50eebcaa9fdf894e801bd2971086de328248d5e8c07cb735af899c5abc7b' 
  AND token = 'U+0oVmMehvtTyh1ehPA10k3WCK4kv3mlbHwWtr1U7NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}