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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4caa06f163ccf4b51efa64bc696d5a431f1874c14dac218e1312f5488e176623' 
  AND token = 'O+kuksh6a9f5NjFCRUBhgjXi0MLwnVQFluNQH6FejXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}