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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '440e52e298a5c53860dd7c13f41f267fc9f6060fd54fe7f54c5e2462096ef579' 
  AND token = '6sTC28zCabkLOEnxjgSjlBg2KN0uQmn7D5VzoqF4Z3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}