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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81811abea8dfa66686c88127ab83195fe553a4accb462e75bac20093e44a8e9' 
  AND token = 'ase+ggDyHUUGJ4KbBE5kGCa/U2MNGmODfto3Sjip77A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}