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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15cbf921a2c64c4d8f84364f567175cb5e31b3aec5c56b6dd8a7b49cd0ab1622' 
  AND token = 'FvNQBICXrPpxwTd9jOfeMDwjvr3bOSZuP6nLgLt2k8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}