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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '276cf8408f2d36f96c94587c009650e23127fe3983644846db044fa0051c0240' 
  AND token = 'DMj+dOaQMt+Dtv6Wv49JMM6hqN7GB72PmRenU+DPV8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}