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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3943dbb8cb8ccc9923df40911b1cbb3f4e59291270607541a77817fd913a1d36' 
  AND token = 'JoJxDrhhjyd8OvEJ6KaLakxELnC7W2dPBPLF6zAxsRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}