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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '496aa7abd88a08b8d4b1fad1549d1e353fb97bbe9d3949954e94fed1b4fd4978' 
  AND token = 'SoILvU3LMP1aeM0oOgaqunrO7DEoBag1GV97/96IrQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}