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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc4004d0207e7056c240bfec2144880e8bce24ff9c0f292059d3bd4a9640bd1f' 
  AND token = 'ZQ4Tc01PChclczaZbyjgwqECcshb54+QUUMQAz+w1Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}