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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed0b55d640155897e5ce666a8577a8ca2d6ec6c9dec3edf8043ed7b967c7c60d' 
  AND token = 'USah7TJYLe6EHVRieChyC9CYA9VVLZdQA9sv1OYlus4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}