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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e8172a2e1c0584314caf3d46134ee9e14e793850fa17c4a2f016be65035e0f' 
  AND token = 'GU/ceJH9QxCYETvMEYDjdXs8jV8xveecEMhASkiNVko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}