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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a55e36dfc2552d9ab32a799d5a0ad1905db811ef3e0983696a5de02763a3cc78' 
  AND token = 'OrN7dX+eRvGh2e/Ik7eQD/6BnqvK6aRfRi+z79AlvWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}