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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a4e85b4ce393153b2b527ad1afab12ede8c7289bf402596ea290e598aefbc1' 
  AND token = 'PNM8VtO/BWm6jv9OLg9jTLK6QHBTkR7rCLlz5QAp7sU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}