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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb76c5bf41835f36a78fb4744b7f8769816d38e5c9ef37fd2e4fab619bedfe5b' 
  AND token = 'X+h1oFMB4uTUyn/R+yPBA0AbNFo4H8XtRZC01S+yx4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}