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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ad4e37723a0bfdae517081361293329be00f0fe8f89cf1fb28971c1db029a98' 
  AND token = 'mb3nejVB+cyAo65tNhNt0DpBsfyjx/+JC3IA0VSPOE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}