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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d848c9a41f80ac6126ae6fdd6b5aa822ece5b30f1f81653b4bc211a6348e15' 
  AND token = 'Izvoo9k3YDG1jeOimnvpU7aONHqQCzNKYvdl1oVFcvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}