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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d18c446c22dbe706f5406363dc325d1f752bbc2e671f7c6b37adb0ac31d1d5c' 
  AND token = 'eQUhuTT6ptc7PicENPs0h2MxvJUxHnvpZJfdnEbtgbY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}